Depends on the power scaling. Preds have died to Bears. Feral killed a Bear with just his own two hands in the trailer. Some Preds have also went & fought Superman, which puts them on Planet Buster levels at minimum. Feral obviously ain’t gonna be cracking the Earth in this movie.
Even more recently we know that canonically the Viking Predator did die to a Human Viking warrior, because Valkyrie showed up to avenge him. Considering Viking is like twice the muscle mass of Feral from what we seen and is even more armored, that’s an impressive feat for whichever Human did it.
I am expecting Feral to be around the level of City Hunter, who did of course die in CQC with Harrigan. Though I suspect (and hope) that Feral’s death comes in the form of a callback to Jungle’s death. At the hands of multiple Traps & Ambush Tactics.
You always have to remember that Power Scaling is a thing in pretty much every franchise. Some are gonna be physical Gods, others are gonna job to Animals. Its the nature of storytelling & showing different individuals in a series. No different from the Saiyans really.
Some Preds die in combat with Earth Animals.
Some Preds go to throw hands with dudes who can move faster than light & benchpress a Planet.